Biochem/physiol Actions

Reversible: yes

Cell permeable: yes

General description

A randomly shuffled Beclin-1 (267-284) peptide made cell-permeable by covalently attaching to HIV-1 Tat protein transduction domain via a diglycine linker. Reported to serve as a suitable control for autophagy-inducing peptides (Cat. nos. 506048 & 506416).

A randomly shuffled Beclin-1 (267-284) peptide made cell-permeable by covalently attaching to HIV-1 Tat protein transduction domain via a diglycine linker. Reported to serve as a suitable control for autophagy-inducing peptides (Cat. nos. 506048 & 506416).Please note that the molecular weight for this compound is batch-specific due to variable water content.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Other Notes

Liu, Y., et al. 2013. Proc. Natl. Acad. Sci. USA110, 20364.Shoji-Kawata, S., et al. 2013. Nature.494, 201.

Packaging

5 mg in Glass bottle

Packaged under inert gas

Sequence

H-Tyr-Gly-Arg-Lys-Lys-Arg-Arg-Gln-Arg-Arg-Arg~Gly-Gly~Val-Gly-Asn-Asp-Phe-Phe-Ile-Asn-His-Glu-Thr-Thr-Gly-Phe-Ala-Thr-Glu-Trp-OH

Warning

Toxicity: Standard Handling (A)